Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1438997 | 1.00 | ERN1 (0.57) | ERN1TDP1ALDH1A1VCAM1MEN1 | |
| SCHEMBL11323164 | 0.82 | TDP1 (0.61) | ERN1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL5157078 | 0.78 | ERN1 (0.64) | ERN1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3799010 | 0.77 | ALDH1A1 (0.48) | ERN1ALDH1A1IDO1 | |
| SCHEMBL42560 | 0.76 | TDP1 (0.67) | ERN1TDP1ALDH1A1VCAM1MAPK1 | |
| SCHEMBL29818700 | 0.74 | ALDH1A1 (0.67) | ERN1TDP1ALDH1A1VCAM1ALDH1A3 | |
| SCHEMBL3787764 | 0.74 | ALDH1A1 (0.67) | ERN1TDP1ALDH1A1VCAM1ALDH1A3 | |
| SCHEMBL155042 | 0.73 | ERN1 (0.57) | ERN1TDP1ALDH1A1VCAM1 | |
| SCHEMBL1710916 | 0.73 | ERN1 (0.57) | ERN1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL13350064 | 0.73 | TDP1 (0.45) | ERN1TDP1ALDH1A1VCAM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305118-B | Synthetic method suitable for industrial production of enggliflozin | 四川科伦药物研究院有限公司 | 2024-04-02 | — | — | CN | disclosed |