Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29818700 | 1.00 | ALDH1A1 (0.67) | ALDH1A1VCAM1HSD17B10TDP1ALDH1A3 | |
| SCHEMBL26908557 | 0.82 | ALDH1A1 (0.47) | ALDH1A1VCAM1HSD17B10TDP1ALDH1A3 | |
| SCHEMBL30493606 | 0.81 | ALDH1A1 (0.67) | ALDH1A1VCAM1HSD17B10TDP1ALDH1A3 | |
| SCHEMBL3122359 | 0.81 | ALDH1A1 (0.67) | ALDH1A1VCAM1HSD17B10TDP1ALDH1A3 | |
| SCHEMBL48577 | 0.80 | ALDH1A1 (1.00) | ALDH1A1VCAM1HSD17B10ALDH1A3KDM4E | |
| SCHEMBL29364412 | 0.80 | ALDH1A1 (1.00) | ALDH1A1VCAM1HSD17B10ALDH1A3KDM4E | |
| SCHEMBL26908606 | 0.80 | ALDH1A1 (0.44) | ALDH1A1VCAM1HSD17B10TDP1ALDH1A3 | |
| Water SCHEMBL28568603 | 0.79 | ALDH1A1 (0.64) | ALDH1A1VCAM1HSD17B10TDP1ALDH1A3 | |
| Hydrochloric Acid SCHEMBL28849470 | 0.78 | ALDH1A1 (0.95) | ALDH1A1VCAM1HSD17B10ALDH1A3KDM4E | |
| SCHEMBL42560 | 0.78 | TDP1 (0.67) | ALDH1A1VCAM1HSD17B10TDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| CN-1146472-C | Catalyst for catalyzing unsymmetrical hetero-Diels-Alder reaction, its preparation and application | 中国科学院上海有机化学研究所 | 2004-04-21 | — | — | CN | disclosed |
| US-4172937-A | REACTION OF A DIALDEHYDE AND DIAMINE IN A PHENOLIC COMPOUND | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885VCAM1 4526/4885HSD17B10 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.