Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714688 | 0.86 | CASP1 (0.46) | CASP1 | |
| SCHEMBL19714665 | 0.82 | CASP1 (0.33) | CASP1 | |
| SCHEMBL1003303 | 0.78 | ADORA1 (0.33) | ADORA1LMNAALDH1A1DHFRKCNH2 | |
| SCHEMBL11569832 | 0.76 | ADORA2A (0.40) | ADORA2AADORA2BADORA1ADORA3TLR8 | |
| SCHEMBL11572610 | 0.76 | ADORA2A (0.40) | ADORA2AADORA2BADORA1ADORA3TLR8 | |
| SCHEMBL28462770 | 0.72 | CASP1 (0.39) | CASP1 | |
| SCHEMBL92739 | 0.72 | KCNH2 (0.46) | ADORA2AADORA2BADORA1ADORA3L3MBTL1 | |
| SCHEMBL8647469 | 0.72 | CASP1 (0.50) | ADORA2AADORA2BADORA1ADORA3TLR8 | |
| SCHEMBL447214 | 0.71 | KMT2A (0.42) | ADORA2AADORA2BADORA1ADORA3LMNA | |
| SCHEMBL1543072 | 0.71 | KMT2A (0.42) | ADORA2AADORA2BADORA1ADORA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |