SCHEMBL1543072

SCHEMBL1543072

CCCCCc1nc(Cl)nc(CCCCC)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.42
KCNH2 Q12809 1/20 0.39
LMNA P02545 2/20 0.38
GPR84 Q9NQS5 1/20 0.38
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
PKM P14618 1/20 0.35
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
TYMP P19971 3/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
CETP P11597 1/20 0.33
MEN1 O00255 1/20 0.32
CASP1 P29466 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28637072 0.98 KMT2A (0.44) KMT2AKCNH2LMNAGPR84ALDH1A1
SCHEMBL447214 0.95 KMT2A (0.42) KMT2AKCNH2LMNAGPR84ALDH1A1
SCHEMBL10992770 0.93 KMT2A (0.44) KMT2AKCNH2LMNAGPR84ALDH1A1
SCHEMBL4405124 0.93 KMT2A (0.44) KMT2AKCNH2LMNAGPR84ALDH1A1
SCHEMBL11417577 0.93 KMT2A (0.44) KMT2AKCNH2LMNAGPR84ALDH1A1
SCHEMBL11413687 0.93 KMT2A (0.44) KMT2AKCNH2LMNAGPR84ALDH1A1
SCHEMBL10911101 0.93 CETP (0.36) KMT2AKCNH2LMNAGPR84ALDH1A1
SCHEMBL1318651 0.88 ALDH1A1 (0.40) KMT2AKCNH2LMNAGPR84ALDH1A1
SCHEMBL92739 0.87 KCNH2 (0.46) KMT2AKCNH2GPR84ALDH1A1HPGD
SCHEMBL8647469 0.86 CASP1 (0.50) KMT2AKCNH2LMNAGPR84ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101260296-A Blue luminous polymer and preparation method thereof HUAIHAI INST TECHNOLOGY (CN) 2008-09-10 CN claimed
US-5438138-A Process for the preparation of mono- and diaryltriazines CIBA-GEIGY CORPORATION (US) 1995-08-01 US claimed
EP-0577559-A2 Process for the preparation of mono- and diaryltriazines CIBA-GEIGY AG (CH) 1994-01-05 EP claimed
CN-116120249-A Novel method for synthesizing s-triazine compound 中昊(大连)化工研究设计院有限公司 2023-05-16 CN disclosed
CN-113260679-A Process for preparing triazine intermediates and process for preparing UV absorbers thereof 巴斯夫欧洲公司 2021-08-13 CN disclosed
US-20160240782-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2016-08-18 US disclosed
US-9353085-B2 Compound for organic electroluminescent device and organic electroluminescent devices using the same E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2016-05-31 US disclosed
EP-2307520-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2015-11-11 EP disclosed
CN-102076818-B Material for organic electroluminescent device MERCK PATENT GMBH 2014-07-02 CN disclosed
US-8592055-B2 Compound for organic electroluminescent device and organic electroluminescent device having the same E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2013-11-26 US disclosed
US-20130048956-A1 COMPOUND FOR ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2013-02-28 US disclosed
US-6242598-B1 NUCLEOPHILIC DISPLACEMENT OF A CYANURIC CHLORIDE ATOM WITH A PHENOLIC MOIETY, A FRIEDEL-CRAFTS REACTION USING A LEWIS ACID, AND REPLACING THE PHENOLIC MOIETY WITH RESORINOL USING A LEWIS ACID OR A PROTIC ACID CATALYSTS CIBA SPECIALTY CHEMICALS CORPORATION 2001-06-05 US disclosed
EP-0497734-B1 Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines CIBA SC HOLDING AG (CH) 2000-05-10 EP disclosed
EP-0941989-A2 Process for the preparation of 2,4-diaryl-6-o-hydroxyphenyl-1,3,5-triazine derivatives in the presence of a protic acid catalyst Ciba SC Holding AG (CH) 1999-09-15 EP disclosed
US-5438138-A Process for the preparation of mono- and diaryltriazines CIBA-GEIGY CORPORATION (US) 1995-08-01 US disclosed
US-5438138-A Process for the preparation of mono- and diaryltriazines CIBA-GEIGY CORPORATION (US) 1995-08-01 US disclosed
EP-0577559-A2 Process for the preparation of mono- and diaryltriazines CIBA-GEIGY AG (CH) 1994-01-05 EP disclosed
EP-0577559-A2 Process for the preparation of mono- and diaryltriazines CIBA-GEIGY AG (CH) 1994-01-05 EP disclosed
US-5182389-A PROCESS FOR THE PREPARATION OF 2-(2',4'-DIHYDROXYPHENYL)-4,6-DIARYL-S-TRIAZINES CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
EP-0497734-A1 Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines CIBA-GEIGY AG (CH) 1992-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160240782-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, SLCO4C1, GJA1 KMT2A 3543/4885KCNH2 85/4885LMNA 1154/4885
US-20130048956-A1 COMPOUND FOR ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME ARL1, RPS4X, AR KMT2A 2523/4885KCNH2 134/4885LMNA 2477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.