Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960220 | 0.82 | MEN1 (0.66) | GPR119MEN1KMT2AABL1RIN1 | |
| SCHEMBL28492673 | 0.81 | GPR119 (0.56) | GPR119MEN1KMT2AABL1RIN1 | |
| SCHEMBL30808533 | 0.77 | RECQL (0.45) | MEN1KMT2AHPGDMAPTPOLB | |
| SCHEMBL5237966 | 0.77 | MAPT (0.57) | GPR119MEN1KMT2AMAPT | |
| SCHEMBL4238923 | 0.77 | CYP3A4 (0.60) | MEN1KMT2AHPGD | |
| SCHEMBL18228469 | 0.77 | GPR119 (0.58) | GPR119KMT2AABL1RIN1HPGD | |
| SCHEMBL6194849 | 0.77 | GPR119 (0.64) | GPR119MEN1KMT2AABL1RIN1 | |
| SCHEMBL28585097 | 0.76 | GPR119 (0.53) | GPR119MEN1KMT2AHPGDPOLB | |
| SCHEMBL7858182 | 0.76 | HPGD (0.68) | GPR119MEN1KMT2AABL1RIN1 | |
| SCHEMBL5053 | 0.76 | HPGD (0.68) | GPR119MEN1KMT2AABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801322-B | Kinase inhibitors for the treatment of central and peripheral nervous system disorders | 迈阿密大学 | 2024-03-15 | — | — | CN | disclosed |