Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28981115 | 0.82 | GPR119 (0.48) | GPR119HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30808538 | 0.81 | GPR119 (0.55) | GPR119HPGDMAPTMEN1KMT2A | |
| SCHEMBL28494646 | 0.81 | MEN1 (0.67) | GPR119CA1CA2HPGDALDH1A1 | |
| SCHEMBL5530954 | 0.78 | CHEK2 (0.67) | GPR119PARP10ALDH1A1 | |
| SCHEMBL13218466 | 0.77 | GPR119 (0.79) | GPR119ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL4240126 | 0.76 | POLB (0.69) | GPR119ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5233751 | 0.76 | L3MBTL1 (0.66) | GPR119ALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL19852529 | 0.76 | HPGD (0.71) | HPGDALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL2077166 | 0.76 | HPGD (0.71) | HPGDALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL21707988 | 0.76 | HPGD (0.71) | HPGDALDH1A1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226808-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |