SCHEMBL30810022

SCHEMBL30810022

C[C@@H]1CN(C(=O)c2ccc(F)cc2Cl)CCN1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 9/20 0.54
ALDH1A1 P00352 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
HSD11B1 P28845 1/20 0.53
NPC1 O15118 1/20 0.51
HRH4 Q9H3N8 1/20 0.47
HPGD P15428 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
RXFP1 Q9HBX9 1/20 0.45
UBE2M P61081 1/20 0.44
DCUN1D1 Q96GG9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30691934 1.00 P2RX7 (0.54) P2RX7ALDH1A1MEN1KMT2AHSD11B1
SCHEMBL31454276 1.00 P2RX7 (0.54) P2RX7ALDH1A1MEN1KMT2AHSD11B1
SCHEMBL31568105 0.84 RXFP1 (0.63) P2RX7ALDH1A1MEN1KMT2AHSD11B1
SCHEMBL9364094 0.78 NPC1 (0.51) ALDH1A1MEN1KMT2AHSD11B1NPC1
SCHEMBL108738 0.75 P2RX7 (0.62) P2RX7HSD11B1NPC1
SCHEMBL31646988 0.75 HSD11B1 (0.56) P2RX7ALDH1A1MEN1KMT2AHSD11B1
SCHEMBL31454267 0.75 HSD11B1 (0.56) P2RX7ALDH1A1MEN1KMT2AHSD11B1
SCHEMBL30009239 0.74 P2RX7 (0.51) P2RX7ALDH1A1MEN1KMT2AHSD11B1
SCHEMBL32664352 0.73 P2RX7 (0.47) P2RX7ALDH1A1MEN1KMT2AHSD11B1
SCHEMBL29266781 0.73 PARP1 (0.46) HRH4HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4561994-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS Genecode (EE) 2025-06-04 EP disclosed
CN-119948015-A Novel sulfonamides and their use as neuroprotective and/or nerve repair agents 基因密码公司 2025-05-06 CN disclosed
WO-2024023284-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2024-02-01 WO disclosed