Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14871014 | 0.79 | EGFR (0.41) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL27368594 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL30810293 | 0.74 | ALDH1A1 (0.76) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL14564097 | 0.74 | ALDH1A1 (0.76) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL30810249 | 0.69 | KDM4E (0.47) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL23796728 | 0.68 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL30032141 | 0.68 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL27368597 | 0.67 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL12991505 | 0.67 | EGFR (0.47) | ALDH1A1FTOMEN1KMT2ATHRB | |
| SCHEMBL4868587 | 0.66 | AKR1C4 (0.58) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583870-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | Mito Biopharma, LLC (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054766-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | MITO BIOPHARMA, LLC (US) | 2024-03-14 | — | — | WO | disclosed |