Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.60 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564097 | 1.00 | ALDH1A1 (0.76) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL9250293 | 0.82 | HSD17B10 (0.61) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL45872 | 0.81 | GABRA1 (0.50) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL30810266 | 0.80 | HPGD (0.50) | ALDH1A1HPGDHSD17B10CA1CA2 | |
| SCHEMBL39260 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL15375739 | 0.79 | HMGB1 (0.48) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL10710661 | 0.79 | AKR1C2 (0.58) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL28727228 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL21986386 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 | |
| SCHEMBL5640021 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583870-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | Mito Biopharma, LLC (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054766-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | MITO BIOPHARMA, LLC (US) | 2024-03-14 | — | — | WO | disclosed |