Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484405 | 1.00 | ALOX5 (0.59) | ALOX5HTR2BCHEK1SNCAHTR7 | |
| SCHEMBL28398312 | 0.91 | SNCA (0.42) | ALOX5SNCACCNB2CDK1CCNB1 | |
| SCHEMBL31362085 | 0.91 | SNCA (0.42) | ALOX5SNCACCNB2CDK1CCNB1 | |
| SCHEMBL2482795 | 0.90 | ALOX5 (0.59) | ALOX5HTR2BCHEK1HTR7 | |
| SCHEMBL28403165 | 0.88 | ALOX5 (0.41) | ALOX5SNCA | |
| SCHEMBL27344875 | 0.84 | CHEK1 (0.44) | ALOX5CHEK1GSK3B | |
| SCHEMBL27344399 | 0.81 | ALDH1A1 (0.44) | ALOX5SNCAGSK3B | |
| SCHEMBL21628225 | 0.81 | SNCA (0.37) | ALOX5SNCA | |
| SCHEMBL28404933 | 0.80 | ABL1 (0.43) | ALOX5SNCA | |
| SCHEMBL21628240 | 0.79 | ALOX5 (0.59) | ALOX5HTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543863-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | University Of Ottawa (CA) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |