Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28398312 | 1.00 | SNCA (0.42) | SNCAALOX5CYP2A6NOS3NOS1 | |
| SCHEMBL28403165 | 0.93 | ALOX5 (0.41) | SNCAALOX5CYP2A6NOS3NOS1 | |
| SCHEMBL30811535 | 0.91 | ALOX5 (0.59) | SNCAALOX5CCNB2CDK1CCNB1 | |
| SCHEMBL2484405 | 0.91 | ALOX5 (0.59) | SNCAALOX5CCNB2CDK1CCNB1 | |
| SCHEMBL21628225 | 0.89 | SNCA (0.37) | SNCAALOX5CYP2A6NOS3NOS1 | |
| SCHEMBL27344399 | 0.89 | ALDH1A1 (0.44) | SNCAALOX5CYP2A6NOS3NOS1 | |
| SCHEMBL27344400 | 0.85 | SNCA (0.61) | SNCACCNB2CDK1CCNB1GSK3B | |
| SCHEMBL27344875 | 0.85 | CHEK1 (0.44) | ALOX5GSK3BPGR | |
| SCHEMBL27344295 | 0.85 | TDP1 (0.37) | SNCAALOX5CYP2A6NOS3NOS1 | |
| SCHEMBL28404933 | 0.83 | ABL1 (0.43) | SNCAALOX5CYP2A6NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115919872-B | Application of tricyclic compound and pharmaceutical composition containing tricyclic compound | 中国药科大学 | 2025-02-07 | — | — | CN | disclosed |