Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24484552 | 1.00 | ALOX5 (0.41) | ALOX5DAOCA1CA2CA7 | |
| SCHEMBL3870286 | 0.86 | ALOX5 (0.59) | ALOX5MEN1KMT2A | |
| SCHEMBL31191637 | 0.86 | ALOX5 (0.59) | ALOX5MEN1KMT2A | |
| SCHEMBL31618797 | 0.84 | ALOX5 (0.57) | ALOX5MEN1KMT2A | |
| SCHEMBL12016686 | 0.80 | CREBBP (0.41) | ALOX5DAOCA1CA2CA7 | |
| SCHEMBL5671412 | 0.80 | HTR5A (0.38) | DAOCA1CA2CA7CA9 | |
| SCHEMBL10981657 | 0.75 | ALOX5 (0.42) | ALOX5MEN1KMT2A | |
| SCHEMBL11505295 | 0.75 | DAO (0.45) | ALOX5DAOCA1CA2CA7 | |
| SCHEMBL29198935 | 0.71 | ALOX5 (0.41) | ALOX5CA1CA2CA7CA9 | |
| SCHEMBL3423393 | 0.70 | AHR (0.43) | ALOX5CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543863-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | University Of Ottawa (CA) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |