Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.38 |
| ▸ | CYBB | P04839 | 1/20 | 0.38 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344289 | 1.00 | KIF11 (0.49) | KIF11ACE2NOX1CYBBNOX3 | |
| SCHEMBL27344284 | 0.94 | ACE2 (0.49) | KIF11ACE2NOX1CYBBNOX3 | |
| SCHEMBL30811571 | 0.94 | ACE2 (0.49) | KIF11ACE2NOX1CYBBNOX3 | |
| SCHEMBL27344291 | 0.94 | ACE2 (0.49) | KIF11ACE2NOX1CYBBNOX3 | |
| SCHEMBL29636462 | 0.91 | ALOX5 (0.41) | KIF11ALOX5NFKB1NFKB2RELA | |
| SCHEMBL21628210 | 0.91 | ALOX5 (0.41) | KIF11ALOX5NFKB1NFKB2RELA | |
| SCHEMBL18448706 | 0.91 | ACE2 (0.45) | KIF11ACE2NOX1CYBBNOX3 | |
| SCHEMBL27344285 | 0.86 | ACE2 (0.54) | KIF11ACE2NOX1CYBBNOX3 | |
| SCHEMBL21628219 | 0.83 | ALOX5 (0.59) | KIF11ALOX5NFKB1NFKB2RELA | |
| SCHEMBL29636432 | 0.83 | ALOX5 (0.59) | KIF11ALOX5NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543863-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | University Of Ottawa (CA) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |