Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21628210 | 1.00 | ALOX5 (0.41) | ALOX5KIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL27344289 | 0.91 | KIF11 (0.49) | ALOX5KIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL21628219 | 0.91 | ALOX5 (0.59) | ALOX5KIF11ALDH1A1TDP1GAA | |
| SCHEMBL30811586 | 0.91 | KIF11 (0.49) | ALOX5KIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL29636432 | 0.91 | ALOX5 (0.59) | ALOX5KIF11ALDH1A1TDP1GAA | |
| SCHEMBL13820938 | 0.88 | NPC1 (0.37) | ALOX5KIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL27344291 | 0.85 | ACE2 (0.49) | ALOX5KIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL27344284 | 0.85 | ACE2 (0.49) | ALOX5KIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL30811571 | 0.85 | ACE2 (0.49) | ALOX5KIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL10131272 | 0.85 | ALDH1A1 (0.34) | KIF11ALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543863-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | University Of Ottawa (CA) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |
| EP-4237498-A1 | COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS | Milliken & Company (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093189-A1 | COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS | MILLIKEN & COMPANY (US) | 2022-05-05 | — | — | WO | disclosed |