Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27381068 | 1.00 | THRA (0.46) | THRATHRBOPRK1PTPN1BRD4 | |
| SCHEMBL27381360 | 0.89 | THRA (0.46) | THRATHRBOPRK1TTREPAS1 | |
| SCHEMBL30812165 | 0.89 | THRA (0.46) | THRATHRBOPRK1TTREPAS1 | |
| SCHEMBL21191011 | 0.85 | BRD4 (0.48) | THRATHRBPTPN1BRD4TTR | |
| SCHEMBL30812137 | 0.83 | MAOB (0.47) | SPHK1 | |
| SCHEMBL27381041 | 0.83 | MAOB (0.47) | SPHK1 | |
| SCHEMBL21191065 | 0.79 | BRD4 (0.54) | BRD4P2RX4 | |
| SCHEMBL27381541 | 0.78 | EPAS1 (0.46) | THRATHRBBRD4EPAS1CYP3A4 | |
| SCHEMBL21190854 | 0.77 | BRD4 (0.50) | PTPN1BRD4EPAS1 | |
| SCHEMBL27381706 | 0.75 | ACHE (0.46) | THRATHRBCYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054956-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |