Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21191011 | 0.86 | BRD4 (0.48) | BRD4EPAS1NR3C1PTPN1CA2 | |
| SCHEMBL15067636 | 0.85 | EPAS1 (0.55) | BRD4EPAS1NR3C1METKDR | |
| SCHEMBL30443821 | 0.85 | EPAS1 (0.55) | BRD4EPAS1NR3C1METKDR | |
| SCHEMBL21681543 | 0.81 | EPAS1 (0.41) | BRD4EPAS1PTPN1KDR | |
| SCHEMBL21190859 | 0.79 | TTR (0.50) | EPAS1NR3C1 | |
| SCHEMBL21190850 | 0.79 | NR3C1 (0.46) | EPAS1SLC6A4NR3C1 | |
| SCHEMBL30812017 | 0.77 | THRA (0.46) | BRD4EPAS1PTPN1 | |
| SCHEMBL27381068 | 0.77 | THRA (0.46) | BRD4EPAS1PTPN1 | |
| SCHEMBL21190858 | 0.77 | SLC6A4 (0.41) | EPAS1SLC6A4NR3C1 | |
| SCHEMBL21191065 | 0.76 | BRD4 (0.54) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |