Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29148269 | 0.99 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| SCHEMBL7253181 | 0.83 | GAA (0.37) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| SCHEMBL30804093 | 0.81 | PPOX (0.50) | PPOXDHODH | |
| SCHEMBL29148286 | 0.81 | LMNA (0.35) | SMN1; SMN2HPGDLMNAMAPTDHODH | |
| SCHEMBL29148242 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| SCHEMBL29148259 | 0.79 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| SCHEMBL25285902 | 0.78 | BAZ2B (0.47) | SMN1; SMN2GAAHPGDLMNAMAPT | |
| SCHEMBL7250626 | 0.78 | LMNA (0.36) | SMN1; SMN2GAAHPGDPOLBPPOX | |
| SCHEMBL29189448 | 0.78 | MAPT (0.41) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| SCHEMBL25243907 | 0.77 | POLB (0.32) | SMN1; SMN2GAAHPGDPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486818-A | N-phenyl thiotriazinone derivative and preparation method and application thereof | 贵州大学 | 2024-02-02 | — | — | CN | disclosed |