Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29430982 | 0.86 | PIN1 (0.47) | PIN1CASP3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29052325 | 0.86 | CASP3 (0.45) | PIN1CASP3MDM4TP53KMT2A | |
| SCHEMBL31453529 | 0.85 | CASP3 (0.45) | PIN1CASP3MDM4TP53KMT2A | |
| SCHEMBL31355420 | 0.84 | CASP3 (0.49) | PIN1CASP3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29051485 | 0.84 | CASP3 (0.49) | PIN1CASP3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30812611 | 0.82 | CASP3 (0.42) | PIN1CASP3MDM4TP53KMT2A | |
| SCHEMBL12944743 | 0.80 | CASP3 (0.50) | PIN1CASP3MDM4TP53KMT2A | |
| SCHEMBL31442823 | 0.80 | CASP3 (0.50) | PIN1CASP3MDM4TP53KMT2A | |
| SCHEMBL22283235 | 0.80 | CASP3 (0.50) | PIN1CASP3MDM4TP53KMT2A | |
| SCHEMBL12094357 | 0.80 | CASP3 (0.50) | PIN1CASP3MDM4TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304299-A | Preparation method of Tirzepatide | 深圳市健元医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |