Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD1 | P21728 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289739 | 1.00 | CYP2D6 (0.37) | CYP2D6CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL5181025 | 0.96 | BCHE (0.36) | CYP2D6CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL5182835 | 0.90 | CYP2D6 (0.38) | CYP2D6CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL2290421 | 0.83 | NR4A2 (0.38) | HRH3NR4A2NR4A1NR4A3RXRA | |
| SCHEMBL5182945 | 0.83 | BCHE (0.38) | CYP2D6CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL2293404 | 0.81 | LMNA (0.45) | CYP2D6CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL30814239 | 0.81 | LMNA (0.45) | CYP2D6CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL5181405 | 0.81 | LMNA (0.45) | CYP2D6CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL5182953 | 0.79 | NR4A2 (0.38) | ADRB2ALDH1A1NR4A2NR4A1NR4A3 | |
| SCHEMBL2290286 | 0.77 | RXRA (0.40) | CHRM2CHRM1DRD2ADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |