Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | MC3R | P41968 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293404 | 1.00 | LMNA (0.45) | LMNACYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL5181405 | 0.96 | LMNA (0.45) | LMNACYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL5182498 | 0.94 | HTR1A (0.48) | LMNACYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL5184457 | 0.90 | HTR1A (0.48) | LMNACYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL5182835 | 0.90 | CYP2D6 (0.38) | LMNACYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL5181121 | 0.83 | MAPK1 (0.39) | HTR1ADRD2CHRM2ADRA2AADORA3 | |
| SCHEMBL5182899 | 0.83 | MAPK1 (0.39) | CYP1A2CYP2D6HTR1ADRD2CHRM2 | |
| SCHEMBL5182945 | 0.83 | BCHE (0.38) | LMNACYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL2289739 | 0.81 | CYP2D6 (0.37) | LMNACYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL30814201 | 0.81 | CYP2D6 (0.37) | LMNACYP1A2CYP2D6CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |