Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627421 | 0.89 | L3MBTL1 (0.54) | MAPTGAATHRBACHEL3MBTL1 | |
| SCHEMBL28622598 | 0.82 | MAPT (0.48) | MAPTGAATHRBACHEL3MBTL1 | |
| SCHEMBL30816313 | 0.82 | MAPT (0.64) | MAPTGAATHRBL3MBTL1KDM4E | |
| SCHEMBL28616298 | 0.81 | KDM4E (0.51) | MAPTTHRBACHEKDM4EALDH1A1 | |
| SCHEMBL28620945 | 0.78 | GPR183 (0.50) | MAPTGAAL3MBTL1KDM4ETDP1 | |
| SCHEMBL28620396 | 0.75 | LMNA (0.48) | MAPTTHRBKDM4ENPC1LMNA | |
| SCHEMBL28619373 | 0.75 | MAPT (0.52) | MAPTGAATHRBKDM4EALDH1A1 | |
| SCHEMBL28634881 | 0.74 | GAA (0.48) | MAPTGAAL3MBTL1KMT2ANPC1 | |
| SCHEMBL28616300 | 0.73 | GPR183 (0.51) | ALDH1A1LMNA | |
| SCHEMBL28620401 | 0.73 | GPR183 (0.55) | MAPTTHRBALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117503772-A | Compound for inhibiting hepatitis B surface antigen and application thereof | 重庆医科大学国际体外诊断研究院 | 2024-02-06 | — | — | CN | disclosed |