Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ESRRA | P11474 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445111 | 0.91 | ALDH1A1 (0.65) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL7566531 | 0.91 | ALDH1A1 (0.65) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL4641784 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL27650719 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL31615593 | 0.80 | ALDH1A1 (0.65) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL17512389 | 0.80 | GAA (0.64) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL28317018 | 0.80 | PDK1 (0.69) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL4641775 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL5734347 | 0.80 | VCAM1 (0.68) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| Veratric Acid Methyl Ester SCHEMBL2371276 | 0.80 | MAPT (0.70) | ALDH1A1HPGDNPSR1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917410-A | Pan-KRAS degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |