Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30817396 | 0.84 | LGMN (0.43) | LGMNMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31198876 | 0.79 | LGMN (0.45) | LGMNKMT2AALDH1A1LMNAHRH3 | |
| SCHEMBL31727337 | 0.76 | CRBN (0.51) | LGMNALDH1A1LMNAPOLB | |
| SCHEMBL615270 | 0.74 | L3MBTL1 (0.43) | LGMNMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL22816236 | 0.73 | LGMN (0.42) | LGMNHRH3F12RORCL3MBTL1 | |
| SCHEMBL6132758 | 0.72 | LGMN (0.52) | LGMNALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL5546662 | 0.71 | POLB (0.55) | LGMNKMT2AALDH1A1LMNAATM | |
| SCHEMBL5539112 | 0.71 | LGMN (0.54) | LGMNMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1982163 | 0.71 | LGMN (0.61) | LGMNMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL974758 | 0.71 | LGMN (0.54) | LGMNMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059808-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |