Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.52 |
| ▸ | HTR3B | O95264 | 4/20 | 0.52 |
| ▸ | HTR3A | P46098 | 4/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198876 | 0.83 | LGMN (0.45) | LGMNADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL6132755 | 0.83 | ADRB1 (0.51) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14117662 | 0.80 | LGMN (0.54) | LGMNADRB1USP2ALDH1A1KDM4E | |
| SCHEMBL974758 | 0.80 | LGMN (0.54) | LGMNALDH1A1KDM4ELMNA | |
| SCHEMBL3795448 | 0.80 | LGMN (0.54) | LGMNALDH1A1KDM4ELMNATSHR | |
| SCHEMBL1982163 | 0.80 | LGMN (0.61) | LGMNUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL5546662 | 0.80 | POLB (0.55) | LGMNADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL5539112 | 0.80 | LGMN (0.54) | LGMNALDH1A1KDM4ELMNA | |
| SCHEMBL31380531 | 0.80 | LGMN (0.54) | LGMNLTA4HALDH1A1KDM4ELMNA | |
| SCHEMBL612022 | 0.79 | LMNA (0.55) | LGMNADRB1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |