SCHEMBL30817489

SCHEMBL30817489

Cc1cn([C@H]2C[C@H](OP(O)(O)=S)[C@@H](CO)O2)c(=O)nc1N

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ RNASE1 P07998 1/20 0.43
▸ DNMT1 P26358 5/20 0.43
▸ ADRB1 P08588 1/20 0.43
▸ TK1 P04183 4/20 0.40
▸ ALB P02768 2/20 0.39
▸ DNMT3B Q9UBC3 1/20 0.39
▸ POLB P06746 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ BLM P54132 1/20 0.38
▸ PMP22 Q01453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19464715 1.00 RNASE1 (0.43) RNASE1DNMT1ADRB1TK1ALB
SCHEMBL17052648 1.00 RNASE1 (0.43) RNASE1DNMT1ADRB1TK1ALB
SCHEMBL17056236 1.00 RNASE1 (0.43) RNASE1DNMT1ADRB1TK1ALB
SCHEMBL23102039 0.92 POLG (0.38) RNASE1DNMT1ADRB1TK1ALB
SCHEMBL6517103 0.92 RNASE1 (0.45) RNASE1DNMT1ADRB1TK1DNMT3B
SCHEMBL10331938 0.92 RNASE1 (0.45) RNASE1DNMT1ADRB1TK1DNMT3B
SCHEMBL16587689 0.90 TK1 (0.36) RNASE1DNMT1ADRB1TK1POLB
SCHEMBL15280815 0.90 TK1 (0.38) RNASE1DNMT1ADRB1TK1
SCHEMBL24517423 0.87 RNASE1 (0.46) RNASE1DNMT1ADRB1TK1ALB
SCHEMBL14773848 0.86 RNASE1 (0.46) RNASE1DNMT1ADRB1TK1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025068557-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF CANAVAN DISEASE CONTERA PHARMA A/S (DK) 2025-04-03 — — WO claimed
EP-4594491-A2 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF CANAVAN DISEASE Contera Pharma A/S (DK) 2025-08-06 — — EP disclosed
WO-2025068557-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF CANAVAN DISEASE CONTERA PHARMA A/S (DK) 2025-04-03 — — WO disclosed
WO-2024068997-A2 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF CANAVAN DISEASE CONTERA PHARMA A/S (DK) 2024-04-04 — — WO disclosed
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