SCHEMBL30817786

SCHEMBL30817786

CC(C)c1nc(-c2cccc(C(C(=O)O)C(=O)O)c2)no1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 4/20 0.46
TDP1 Q9NUW8 1/20 0.44
NPY2R P49146 1/20 0.43
PTPN1 P18031 1/20 0.43
S1PR1 P21453 1/20 0.43
MMP12 P39900 1/20 0.43
ACACB O00763 5/20 0.43
PPARD Q03181 2/20 0.43
PPARA Q07869 2/20 0.43
HTT P42858 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
DPP4 P27487 1/20 0.42
DPP7 Q9UHL4 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29176876 1.00 S1PR3 (0.46) S1PR3TDP1NPY2RPTPN1S1PR1
SCHEMBL30817792 0.88 S1PR3 (0.43) S1PR3TDP1NPY2RPTPN1S1PR1
SCHEMBL29176836 0.88 S1PR3 (0.43) S1PR3TDP1NPY2RPTPN1S1PR1
SCHEMBL29176864 0.87 S1PR3 (0.46) S1PR3TDP1PTPN1S1PR1ACACB
SCHEMBL30817773 0.87 S1PR3 (0.46) S1PR3TDP1PTPN1S1PR1ACACB
SCHEMBL29176830 0.84 AAK1 (0.49) S1PR3NPY2RPTPN1S1PR1ACACB
SCHEMBL29176858 0.84 L3MBTL1 (0.62) S1PR3MMP12HTTNPSR1
SCHEMBL30817778 0.84 L3MBTL1 (0.62) S1PR3MMP12HTTNPSR1
SCHEMBL60146 0.82 L3MBTL1 (0.58) S1PR3TDP1HTTDPP4DPP7
SCHEMBL30817754 0.82 NR1H4 (0.56) S1PR3TDP1S1PR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720535-B Pyrido [1, 2-a ] pyrimidine mesoionic derivative containing 1,2, 4-oxadiazole structure, and preparation and application thereof 贵州大学 2025-05-13 CN disclosed
CN-117720535-A Pyrido [1,2-a ] pyrimidine mesoionic derivative containing 1,2, 4-oxadiazole structure, and preparation and application thereof 贵州大学 2024-03-19 CN disclosed