SCHEMBL30817792

SCHEMBL30817792

CC(C)c1nc(-c2cccc(C(C(=O)Cl)C(=O)Cl)c2)no1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 6/20 0.43
S1PR1 P21453 2/20 0.42
HTT P42858 2/20 0.42
AAK1 Q2M2I8 3/20 0.41
S1PR2 O95136 1/20 0.41
S1PR4 O95977 1/20 0.41
S1PR5 Q9H228 1/20 0.41
NPY2R P49146 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
DPP4 P27487 1/20 0.40
DPP7 Q9UHL4 1/20 0.40
PTPN1 P18031 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KCNT1 Q5JUK3 1/20 0.39
HPGDS O60760 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29176836 1.00 S1PR3 (0.43) S1PR3S1PR1HTTAAK1S1PR2
SCHEMBL30817786 0.88 S1PR3 (0.46) S1PR3S1PR1HTTNPY2RTDP1
SCHEMBL29176876 0.88 S1PR3 (0.46) S1PR3S1PR1HTTNPY2RTDP1
SCHEMBL30817756 0.88 S1PR3 (0.43) S1PR3S1PR1HTTS1PR2S1PR4
SCHEMBL29176866 0.88 S1PR3 (0.43) S1PR3S1PR1HTTS1PR2S1PR4
SCHEMBL30817775 0.84 L3MBTL1 (0.60) S1PR3HTTL3MBTL1NPSR1
SCHEMBL29176852 0.84 L3MBTL1 (0.60) S1PR3HTTL3MBTL1NPSR1
SCHEMBL29176830 0.83 AAK1 (0.49) S1PR3S1PR1HTTAAK1NPY2R
SCHEMBL30817777 0.82 HPGDS (0.41) S1PR3S1PR1HTTL3MBTL1NPSR1
SCHEMBL29176853 0.82 HPGDS (0.41) S1PR3S1PR1HTTL3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720535-B Pyrido [1, 2-a ] pyrimidine mesoionic derivative containing 1,2, 4-oxadiazole structure, and preparation and application thereof 贵州大学 2025-05-13 CN disclosed
CN-117720535-A Pyrido [1,2-a ] pyrimidine mesoionic derivative containing 1,2, 4-oxadiazole structure, and preparation and application thereof 贵州大学 2024-03-19 CN disclosed