SCHEMBL30819206

SCHEMBL30819206

COc1c(O)cc2ccc(=O)oc2c1OC

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 0.73
CA9 Q16790 8/20 0.73
CA1 P00915 7/20 0.73
CA7 P43166 7/20 0.73
CA13 Q8N1Q1 7/20 0.73
KDM4E B2RXH2 8/20 0.71
HSD17B10 Q99714 7/20 0.71
ALDH1A1 P00352 6/20 0.71
HPGD P15428 5/20 0.71
CYP3A4 P08684 5/20 0.62
CYP1A2 P05177 4/20 0.62
CYP2C19 P33261 3/20 0.62
CYP2D6 P10635 3/20 0.62
MAPK1 P28482 2/20 0.62
CYP2A6 P11509 2/20 0.62
MAOA P21397 2/20 0.62
ACHE P22303 2/20 0.62
TSHR P16473 1/20 0.62
PDE4A P27815 1/20 0.62
SLC6A3 Q01959 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28324995 1.00 CA12 (0.73) CA12CA9CA1CA7CA13
SCHEMBL4659463 0.88 CA9 (0.77) CA12CA9CA1CA7CA13
SCHEMBL30599780 0.84 CA9 (1.00) CA12CA9CA1CA7CA13
SCHEMBL11434277 0.84 CA9 (1.00) CA12CA9CA1CA7CA13
SCHEMBL5427865 0.83 CA9 (0.64) CA12CA9CA1CA7CA13
Fraxidin Methyl Ether SCHEMBL2464275 0.83 CA9 (1.00) CA12CA9CA1CA7CA13
SCHEMBL30098746 0.82 CA9 (0.78) CA12CA9CA1CA7CA13
SCHEMBL3924718 0.82 CA9 (0.78) CA12CA9CA1CA7CA13
SCHEMBL29396102 0.79 CA9 (1.00) CA12CA9CA1CA7CA13
SCHEMBL3190311 0.79 CA9 (1.00) CA12CA9CA1CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117740961-A Compound analysis method of liquorice and liquorice probiotics fermentation preparation 北京中医药大学 2024-03-22 CN disclosed