Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670253 | 0.82 | AKR1C3 (0.45) | HTTNPSR1KDM4ESLC6A2SLC6A4 | |
| SCHEMBL2433493 | 0.78 | POLB (0.40) | LMNAHTTNPSR1KDM4EHPGD | |
| SCHEMBL6807941 | 0.77 | KDM4E (0.42) | LMNANPSR1KDM4ESLC6A2SLC6A4 | |
| SCHEMBL28809532 | 0.74 | KDM4E (0.39) | LMNANPSR1KDM4ESLC6A2SLC6A4 | |
| SCHEMBL7289944 | 0.72 | KDM4E (0.38) | LMNAHTTNPSR1KDM4ESLC6A2 | |
| SCHEMBL9665247 | 0.72 | HTT (0.40) | LMNAHTTNPSR1TSHRMEN1 | |
| SCHEMBL26898446 | 0.71 | ALDH1A1 (0.50) | LMNATDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8703909 | 0.70 | PPARA (0.32) | AKR1C3AKR1C2 | |
| SCHEMBL19206272 | 0.69 | TDP1 (0.52) | TDP1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL29920958 | 0.69 | TDP1 (0.52) | TDP1HPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3945091-B1 | NOVEL VDAC1 INHIBITORS | ABARCEO AB (SE) | 2024-01-03 | — | — | EP | claimed |