Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819282 | 0.82 | LMNA (0.37) | AKR1C3AKR1C2SMN1; SMN2HTTNPSR1 | |
| SCHEMBL564831 | 0.78 | AKR1C3 (0.58) | AKR1C3AKR1C2AKR1C1PTGS1HTT | |
| SCHEMBL510474 | 0.76 | SRC (0.44) | AKR1C3AKR1C2AKR1C1PTGS1SMN1; SMN2 | |
| SCHEMBL11527109 | 0.75 | ALDH1A1 (0.46) | AKR1C3AKR1C2AKR1C1SMN1; SMN2HTT | |
| SCHEMBL8703909 | 0.74 | PPARA (0.32) | AKR1C3AKR1C2L3MBTL1 | |
| SCHEMBL8708090 | 0.74 | PPARA (0.34) | AKR1C3AKR1C2L3MBTL1 | |
| SCHEMBL6806673 | 0.74 | KDM4E (0.42) | NPSR1KDM4EL3MBTL1ALDH1A1SLC6A2 | |
| SCHEMBL3836130 | 0.73 | AKR1C3 (0.35) | AKR1C3AKR1C2AKR1C1PTGS1SMN1; SMN2 | |
| SCHEMBL21269842 | 0.72 | KDM4E (0.41) | NPSR1KDM4EL3MBTL1ALDH1A1SLC6A2 | |
| SCHEMBL7146446 | 0.72 | PTGS2 (0.41) | AKR1C3AKR1C2PTGS1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511707-B1 | PROCESS FOR PRODUCING AROMATIC COMPOUNDS BY FRIEDEL-CRAFTS REACTION | SHOWA DENKO KK (JP) | 2010-05-19 | — | — | EP | disclosed |
| US-7115782-B2 | Process for producing aromatic compounds by Friedel-Crafts reaction | SHOWA DENKO K.K. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20050222457-A1 | Process for producing aromatic compounds by friedel-crafts reaction | SHOWA DENKO K.K. (JP) | 2005-10-06 | — | — | US | disclosed |
| EP-1511707-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUNDS BY FRIEDEL-CRAFTS REACTION | Showa Denko K.K. (JP) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003101925-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUNDS BY FRIEDEL-CRAFTS REACTION | SHOWA DENKO K. K. (JP) | 2003-12-11 | — | — | WO | disclosed |
| US-4531008-A | Insecticide, miticide | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-07-23 | — | — | US | disclosed |
| US-4266074-A | SUBSTITUTED PHENYL BUTENYL ACETATES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1981-05-05 | — | — | US | disclosed |
| US-4062968-A | MITICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-12-13 | — | — | US | disclosed |
| US-4058622-A | Substituted phenyl acetate, insecticidal composition and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-11-15 | — | — | US | disclosed |
| US-4039680-A | SULFUR CONTAINING HETEROCYCLES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-08-02 | — | — | US | disclosed |
| US-4031235-A | Insecticidal substituted acetate compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-06-21 | — | — | US | disclosed |
| US-3996244-A | Insecticidal esters of substituted furan methanol | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222457-A1 | Process for producing aromatic compounds by friedel-crafts reaction | PAH, DDC, TYR | AKR1C3 656/4885AKR1C2 505/4885AKR1C1 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.