⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142876 | 0.75 | — | — | |
| SCHEMBL28903109 | 0.74 | — | — | |
| SCHEMBL14244082 | 0.66 | FDPS (0.32) | — | |
| SCHEMBL3081462 | 0.65 | — | — | |
| SCHEMBL12999093 | 0.64 | KDM4E (0.31) | — | |
| SCHEMBL27710715 | 0.62 | NPSR1 (0.35) | — | |
| SCHEMBL27710716 | 0.62 | — | — | |
| SCHEMBL9254732 | 0.62 | MAPK1 (0.46) | — | |
| SCHEMBL6226264 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL28478328 | 0.58 | PPARD (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061128-B | Process for preparing diisopropyl ((1- (hydroxymethyl) -cyclopropyl) oxy) methylphosphonate | LG LIFE SCIENCES LTD | 2010-10-06 | — | — | CN | disclosed |
| US-7795463-B2 | Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate | LG LIFE SCIENCES LTD. (KR) | 2010-09-14 | — | — | US | disclosed |
| US-7723319-B2 | Acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCES LTD. (KR) | 2010-05-25 | — | — | US | disclosed |
| US-20090187019-A1 | Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate | LG LIFE SCIENCE LTD. (KR) | 2009-07-23 | — | — | US | disclosed |
| EP-1765838-A4 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD (KR) | 2009-05-27 | — | — | EP | disclosed |
| CN-101061128-A | Process for preparing di-isopropyl ((1(hydroxymethyl)-cyclopropyl)oxy) methylphosphonate | LG LIFE SCIENCES LTD (KR) | 2007-10-24 | — | — | CN | disclosed |
| EP-1765838-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG Life Sciences Ltd. (KR) | 2007-03-28 | — | — | EP | disclosed |
| US-20060052346-A1 | Nucleoside phosphonate derivatives useful in the treatment of HIV infections | LG LIFE SCIENCES LTD. (KR) | 2006-03-09 | — | — | US | disclosed |
| WO-2006004330-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD. (KR) | 2006-01-12 | — | — | WO | disclosed |