Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254732 | 0.73 | MAPK1 (0.46) | FDPS | |
| SCHEMBL13269096 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL6252620 | 0.71 | ALDH1A1 (0.36) | ALDH1A1FDPS | |
| SCHEMBL6004458 | 0.69 | — | — | |
| SCHEMBL31679042 | 0.65 | — | — | |
| SCHEMBL6833594 | 0.64 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL4098286 | 0.63 | PTPN5 (0.32) | — | |
| SCHEMBL23387515 | 0.61 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL28860509 | 0.61 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL11330109 | 0.60 | ALDH1A1 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187507-B2 | Acyclic nucleoside phosphonate derivatives and medical uses thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2015-11-17 | — | — | US | disclosed |
| EP-1497304-B1 | DUAL-LABELED NUCLEOTIDES | CATALYST ASSETS LLC (US) | 2014-06-25 | — | — | EP | disclosed |
| US-20120322764-A1 | Acyclic Nucleoside Phosphonate Derivatives and Medical Uses Thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2012-12-20 | — | — | US | disclosed |
| EP-2511281-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES AND MEDICINE USES THEREOF | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China (CN) | 2012-10-17 | — | — | EP | disclosed |
| US-6858393-B1 | Chain terminators for DNA synthesis | STRATAGENE CALIFORNIA (US) | 2005-02-22 | — | — | US | disclosed |
| EP-1497304-A2 | DUAL-LABELED NUCLEOTIDES | Stratagene California (US) | 2005-01-19 | — | — | EP | disclosed |
| US-20040014096-A1 | Dual-labeled nucleotides | STRATAGENE | 2004-01-22 | — | — | US | disclosed |
| WO-2003087302-A2 | DUAL-LABELED NUCLEOTIDES | STRATAGENE (US) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322764-A1 | Acyclic Nucleoside Phosphonate Derivatives and Medical Uses Thereof | PNP, ENPP3, MTAP | ALDH1A1 2471/4885FDPS 1063/4885 |
| US-20040014096-A1 | Dual-labeled nucleotides | NT5C2, DUT, NT5E | ALDH1A1 1493/4885FDPS 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.