Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22091847 | 0.93 | KIF11 (0.43) | KIF11CYP2C9CYP2C19ALOX15TSHR | |
| SCHEMBL29805216 | 0.93 | KIF11 (0.43) | KIF11CYP2C9CYP2C19ALOX15TSHR | |
| SCHEMBL9665518 | 0.76 | KIF11 (0.39) | KIF11CYP2C9CYP2C19ALOX15TSHR | |
| SCHEMBL8586505 | 0.73 | KIF11 (0.36) | KIF11CYP2C9CYP2C19SLC6A1TK1 | |
| SCHEMBL188157 | 0.73 | KIF11 (0.42) | KIF11CYP2C9CYP2C19ALOX15TSHR | |
| SCHEMBL7055772 | 0.73 | KIF11 (0.39) | KIF11ALDH1A1 | |
| SCHEMBL31603306 | 0.72 | KIF11 (0.41) | KIF11CYP2C9CYP2C19ALOX15TSHR | |
| SCHEMBL26699924 | 0.70 | KIF11 (0.40) | KIF11CYP2C9CYP2C19ALOX15TSHR | |
| SCHEMBL25764027 | 0.70 | KIF11 (0.43) | KIF11CYP2C9CYP2C19ALOX15TSHR | |
| SCHEMBL6241174 | 0.70 | KIF11 (0.56) | KIF11CYP2C9CYP2C19ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795463-B2 | Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate | LG LIFE SCIENCES LTD. (KR) | 2010-09-14 | — | — | US | claimed |
| JP-4422183-B2 | — | — | 2010-02-24 | — | — | JP | claimed |
| US-20090187019-A1 | Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate | LG LIFE SCIENCE LTD. (KR) | 2009-07-23 | — | — | US | claimed |
| EP-1765838-A4 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD (KR) | 2009-05-27 | — | — | EP | claimed |
| JP-2008505066-A | — | — | 2008-02-21 | — | — | JP | claimed |
| EP-1765838-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG Life Sciences Ltd. (KR) | 2007-03-28 | — | — | EP | claimed |
| WO-2006004330-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD. (KR) | 2006-01-12 | — | — | WO | claimed |
| US-20100305364-A1 | PROCESS FOR PREPARING DIISOPROPYL((1-(HYDROXYMETHYL)-CYCLOPROPYL)OXY)METHYLPHOSPHONATE | YOON SUK-KYOON | 2010-12-02 | — | — | US | disclosed |
| US-7795463-B2 | Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate | LG LIFE SCIENCES LTD. (KR) | 2010-09-14 | — | — | US | disclosed |
| US-7795463-B2 | Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate | LG LIFE SCIENCES LTD. (KR) | 2010-09-14 | — | — | US | disclosed |
| US-20090187019-A1 | Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate | LG LIFE SCIENCE LTD. (KR) | 2009-07-23 | — | — | US | disclosed |
| EP-1765838-A4 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD (KR) | 2009-05-27 | — | — | EP | disclosed |
| EP-1765838-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG Life Sciences Ltd. (KR) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006004330-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD. (KR) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305364-A1 | PROCESS FOR PREPARING DIISOPROPYL((1-(HYDROXYMETHYL)-CYCLOPROPYL)OXY)METHYLPHOSPHONATE | DHPS, ITPA, DCPS | KIF11 3491/4885CYP2C9 159/4885CYP2C19 260/4885 |
| US-20090187019-A1 | Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate | DHPS, ITPA, DCPS | KIF11 3491/4885CYP2C9 159/4885CYP2C19 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.