Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | TYR | P14679 | 1/20 | 0.60 |
| ▸ | DAO | P14920 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene SCHEMBL28175555 | 0.89 | MAOB (0.53) | MAOBHPGDSMN1; SMN2TYRDAO | |
| SCHEMBL7124845 | 0.80 | MIF (0.70) | MAOBHPGDSMN1; SMN2TYRDAO | |
| SCHEMBL29517170 | 0.78 | RAB9A (0.78) | MAOBHPGDSMN1; SMN2TYRDAO | |
| SCHEMBL15842521 | 0.78 | MAOB (0.72) | MAOBKDM4EALDH1A1CA12CA9 | |
| SCHEMBL4632815 | 0.77 | HPGD (0.62) | MAOBHPGDSMN1; SMN2TYRDAO | |
| SCHEMBL15842623 | 0.76 | HPGD (0.56) | MAOBHPGDSMN1; SMN2TYRDAO | |
| SCHEMBL7117863 | 0.76 | KDM4E (0.60) | MAOBHPGDSMN1; SMN2POLBKDM4E | |
| SCHEMBL15843061 | 0.76 | MAOB (0.64) | MAOBDAOKDM4EALDH1A1CA12 | |
| SCHEMBL9643651 | 0.75 | HPGD (0.60) | MAOBHPGDSMN1; SMN2TYRDAO | |
| SCHEMBL95179 | 0.75 | SMN1; SMN2 (1.00) | MAOBHPGDSMN1; SMN2TYRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120165029-A | All-solid-state lithium metal battery and preparation method thereof | 中国科学院上海高等研究院 | 2025-06-17 | — | — | CN | claimed |
| CN-108598533-B | Coumarin-based photocyclization crosslinking sulfonated polyimide proton exchange membrane and preparation method thereof | 同济大学 | 2020-11-03 | — | — | CN | claimed |
| CN-105541772-B | A kind of preparation method of 3- chlorocoumarin analog derivative | 广西大学 | 2018-12-28 | — | — | CN | claimed |
| CN-105693705-B | Azoles alcohol compound based on cumarin and its preparation method and application | 西南大学 | 2018-12-28 | — | — | CN | claimed |
| CN-108697657-A | Ultraviolet-curable hydrogel resin for transdermal administration, hydrogel, and poultice containing same | Icure药品株式会社 | 2018-10-23 | — | — | CN | claimed |
| CN-108598533-A | Cyclization cross-linked polyimide proton exchange membrane based on cumarin and preparation method thereof | 同济大学 | 2018-09-28 | — | — | CN | claimed |
| US-10081706-B2 | Side-chain-functionalized polyhydroxyalkanoate materials | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-09-25 | — | — | US | claimed |
| US-20180265631-A1 | SIDE-CHAIN-FUNCTIONALIZED POLYHYDROXYALKANOATE MATERIALS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-09-20 | — | — | US | claimed |
| CN-108484387-A | A kind of preparation method of Mediben | 盐城工学院 | 2018-09-04 | — | — | CN | claimed |
| US-20180186928-A1 | SIDE-CHAIN-FUNCTIONALIZED POLYHYDROXYALKANOATE MATERIALS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-07-05 | — | — | US | claimed |
| US-9127092-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | claimed |
| CN-103554074-B | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2015-03-25 | — | — | CN | claimed |
| US-20140187725-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | claimed |
| CN-103554074-A | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2014-02-05 | — | — | CN | claimed |
| WO-2010138084-A1 | CRYSTAL STRUCTURE OF CAP-FREE HUMAN eIF4E | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-12-02 | — | — | WO | claimed |
| WO-2007057428-A1 | CHROMOPHORE CONTAINING LIGANDS FOR CHARACTERISATION OF RECEPTORS FOR BINDING AND ACTIVATION | EPFL - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2007-05-24 | — | — | WO | claimed |
| EP-1754480-A2 | Compositions comprising phospholipase c inhibitors and methods for enhancing paracellular permeability across epithelial and endothelial barriers | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1379235-A2 | COMPOSITIONS AND METHODS FOR ENHANCING PARACELLULAR PERMEABILITY ACROSS EPITHELIAL AND ENDOTHELIAL BARRIERS | University of North Carolina at Chapel Hill et al. (US) | 2004-01-14 | — | — | EP | claimed |
| US-20020115641-A1 | Compositions and methods for enhancing paracellular permeability across epithelial and endothelial barriers | THAKKER DHIREN R (US) | 2002-08-22 | — | — | US | claimed |
| WO-2002030408-A2 | COMPOSITIONS COMPRISING PHOSPHOLIPASE C INHIBITORS AND METHODS FOR ENHANCING PARACELLULAR PERMEABILITY ACROSS EPITHELIAL AND ENDOTHELIAL BARRIERS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2002-04-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115641-A1 | Compositions and methods for enhancing paracellular permeability across epithelial and endothelial barriers | LIPG, FABP2, PLA2G2A | MAOB 988/4885HPGD 415/4885SMN1; SMN2 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.