Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.48 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859843 | 0.89 | PDCD1 (0.53) | SMN1; SMN2TDP1MEN1KMT2APDCD1 | |
| SCHEMBL15283274 | 0.83 | GAA (0.76) | GAAMAPTSIGMAR1BCHETDP1 | |
| SCHEMBL177039 | 0.82 | MEN1 (0.73) | GAAMAPTSMN1; SMN2SIGMAR1TDP1 | |
| SCHEMBL19401259 | 0.82 | MEN1 (0.73) | GAAMAPTSMN1; SMN2SIGMAR1TDP1 | |
| SCHEMBL21049878 | 0.82 | GAA (0.63) | GAAMAPTSIGMAR1BCHETDP1 | |
| Diethanolamine SCHEMBL5343789 | 0.81 | GAA (0.74) | GAAMAPTSMN1; SMN2SIGMAR1BCHE | |
| Ammonia Solution, Strong SCHEMBL15859332 | 0.81 | GAA (0.73) | GAAMAPTSIGMAR1BCHETDP1 | |
| Hydrochloric Acid SCHEMBL6897315 | 0.81 | SMN1; SMN2 (0.72) | GAAMAPTSMN1; SMN2SIGMAR1TDP1 | |
| Bromide SCHEMBL11864024 | 0.81 | MEN1 (0.70) | GAAMAPTSMN1; SMN2SIGMAR1TDP1 | |
| SCHEMBL7023370 | 0.80 | ENPP2 (0.47) | SMN1; SMN2TDP1MEN1KMT2APDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424160-B | Novel P62 ligand compound and composition for preventing, improving or treating protein conformational diseases comprising the same | 奧土择破利悟株式会社 | 2024-03-08 | — | — | CN | claimed |
| CN-112424160-B | Novel P62 ligand compound and composition for preventing, improving or treating protein conformational diseases comprising the same | 奧土择破利悟株式会社 | 2024-03-08 | — | — | CN | disclosed |