Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14149848 | 0.83 | SMN1; SMN2 (0.54) | LMNAHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5947523 | 0.83 | CYP1A2 (0.56) | HTTSMN1; SMN2ALDH1A1KDM4EFDFT1 | |
| SCHEMBL21634323 | 0.83 | MEN1 (0.65) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13973310 | 0.82 | ALDH1A1 (0.57) | LMNAHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5947215 | 0.82 | BCHE (0.62) | LMNAHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL21634276 | 0.81 | MEN1 (0.62) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5312844 | 0.80 | LMNA (0.60) | LMNAALDH1A1PPARGPPARAFDFT1 | |
| SCHEMBL30821448 | 0.80 | FFAR1 (0.61) | LMNAHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30821586 | 0.80 | KMT2A (0.51) | LMNAHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2356108 | 0.80 | LMNA (0.59) | LMNAALDH1A1PPARGPPARAFDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424160-B | Novel P62 ligand compound and composition for preventing, improving or treating protein conformational diseases comprising the same | 奧土择破利悟株式会社 | 2024-03-08 | — | — | CN | claimed |
| CN-112424160-B | Novel P62 ligand compound and composition for preventing, improving or treating protein conformational diseases comprising the same | 奧土择破利悟株式会社 | 2024-03-08 | — | — | CN | disclosed |