Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13973346 | 0.88 | ALDH1A1 (0.50) | ALDH1A1HTTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL8278009 | 0.87 | KDM4E (0.68) | ALDH1A1HTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13973034 | 0.87 | ALDH1A1 (0.52) | ALDH1A1HTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL14266673 | 0.86 | KDM4E (0.76) | ALDH1A1HTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13973181 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL14149848 | 0.86 | SMN1; SMN2 (0.54) | ALDH1A1HTTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL13948890 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HTTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL13406682 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HTTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL30821649 | 0.82 | LMNA (0.54) | ALDH1A1HTTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL8241107 | 0.82 | ALDH1A1 (0.62) | ALDH1A1HTTSMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090011977-A1 | Novel Lipopeptides as Antibacterial Agents | HILL JASON | 2009-01-08 | — | — | US | disclosed |
| US-7408025-B2 | Lipopeptides as antibacterial agents | CUBIST PHARMACEUTICALS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090011977-A1 | Novel Lipopeptides as Antibacterial Agents | CLPTM1, NGLY1, VIP | ALDH1A1 4742/4885HTT 2832/4885SMN1; SMN2 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.