SCHEMBL3082182

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3087638	0.99	HRH3 (0.56)	HRH3CYP2D6HPGDKMT2ARAB9A
	SCHEMBL3090707	0.91	HRH3 (0.63)	HRH3CYP2D6RAB9ASMN1; SMN2PDE3B
	SCHEMBL3087404	0.86	HRH3 (0.62)	HRH3CYP2D6
	SCHEMBL3082479	0.86	HRH3 (0.59)	HRH3CYP2D6HPGDRAB9ANPSR1
	SCHEMBL13635989	0.83	PDE3B (0.57)	HRH3CYP2D6HPGDKMT2ARAB9A
	SCHEMBL3090978	0.83	HRH3 (0.61)	HRH3CYP2D6
	SCHEMBL14642433	0.82	HRH3 (0.62)	HRH3CYP2D6
	SCHEMBL3077685	0.82	HRH3 (0.50)	HRH3CYP2D6
	SCHEMBL3087259	0.82	BRD4 (0.55)	HRH3CYP2D6PDE3BPDE3A
	SCHEMBL2821544	0.81	HRH3 (0.64)	HRH3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.