Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28839137 | 0.89 | TSHR (0.48) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28400302 | 0.87 | DAO (0.50) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL5575651 | 0.87 | DAO (0.50) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11043492 | 0.85 | DAO (0.52) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11043488 | 0.85 | DAO (0.52) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1864558 | 0.80 | LMNA (0.58) | DAOTSHRNAPRTALDH1A1MAPT | |
| Benzoic Acid SCHEMBL578126 | 0.80 | TSHR (0.74) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2762272 | 0.80 | TSHR (0.74) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL29286711 | 0.80 | TSHR (0.74) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28386505 | 0.78 | TSHR (0.64) | DAOTSHRNAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756970-A | Catalyst for butene-1 polymerization and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | disclosed |