Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 3/20 | 0.41 |
| ▸ | F3 | P13726 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL5575651 | 1.00 | DAO (0.50) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL30822818 | 0.87 | DAO (0.52) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL10540717 | 0.81 | TSHR (0.54) | DAOTSHRNAPRTCES2CES1 | |
| Cis-3-Hexenol SCHEMBL28144390 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| Salicylic Acid SCHEMBL1291827 | 0.80 | ALDH1A1 (0.56) | TSHRNAPRTALDH1A1CYP19A1PPARG | |
| Salicylic Acid SCHEMBL28299839 | 0.80 | ALDH1A1 (0.56) | TSHRNAPRTALDH1A1CYP19A1PPARG | |
| Phenylacetic Acid SCHEMBL28222581 | 0.79 | AKR1B1 (0.57) | TSHRCES2CES1ALDH1A1CYP19A1 | |
| Benzoic Acid SCHEMBL1864558 | 0.79 | LMNA (0.58) | DAOTSHRNAPRTALDH1A1MAPT | |
| Benzoic Acid SCHEMBL897140 | 0.78 | TSHR (0.67) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28407988 | 0.78 | TSHR (0.67) | DAOTSHRNAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115969741-B | Jasmine flower wax and/or jasmine flower absolute oil composition and application thereof | 水羊化妆品制造有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-119060238-A | Drag reducer, preparation method thereof and low-damage desorption-promoting fracturing fluid for coal-rock gas well | 四川申和新材料科技有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-115969741-A | Jasmine flower wax and/or jasmine flower absolute oil composition and application thereof | 水羊化妆品制造有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-111738548-B | Jasmine tea aroma quality evaluation method and application thereof | 福建省农业科学院农业生物资源研究所 | 2023-04-07 | — | — | CN | claimed |
| CN-111738548-A | Jasmine tea aroma quality evaluation method and application thereof | 福建省农业科学院农业生物资源研究所 | 2020-10-02 | — | — | CN | claimed |
| CN-119886583-A | Jasmine tea flavor quality prediction method of extreme learning machine | 常熟理工学院 | 2025-04-25 | — | — | CN | disclosed |
| CN-115969741-B | Jasmine flower wax and/or jasmine flower absolute oil composition and application thereof | 水羊化妆品制造有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119060238-A | Drag reducer, preparation method thereof and low-damage desorption-promoting fracturing fluid for coal-rock gas well | 四川申和新材料科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-116098311-B | Filling material for giving jasmine fragrance taste to cigarettes and preparation method and application thereof | 广东中烟工业有限责任公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117770325-A | Flower-fragrance type Yihongfu tea and preparation method thereof | 宜昌茶业集团有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-116930392-A | Method for evaluating quality of honeysuckle dew based on gas phase characteristic spectrum | 湖北省药品监督检验研究院 | 2023-10-24 | — | — | CN | disclosed |
| CN-116098311-A | Filling material for giving jasmine fragrance taste to cigarettes and preparation method and application thereof | 广东中烟工业有限责任公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-115969741-A | Jasmine flower wax and/or jasmine flower absolute oil composition and application thereof | 水羊化妆品制造有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-111738548-B | Jasmine tea aroma quality evaluation method and application thereof | 福建省农业科学院农业生物资源研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-111738548-B | Jasmine tea aroma quality evaluation method and application thereof | 福建省农业科学院农业生物资源研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-112961745-B | Preparation method of jasmine banana fruit wine | 广西壮族自治区农业科学院 | 2023-03-17 | — | — | CN | disclosed |
| CN-112961745-A | Preparation method of jasmine banana fruit wine | 广西壮族自治区农业科学院 | 2021-06-15 | — | — | CN | disclosed |
| CN-111738548-A | Jasmine tea aroma quality evaluation method and application thereof | 福建省农业科学院农业生物资源研究所 | 2020-10-02 | — | — | CN | disclosed |
| CN-111738548-A | Jasmine tea aroma quality evaluation method and application thereof | 福建省农业科学院农业生物资源研究所 | 2020-10-02 | — | — | CN | disclosed |
| CN-110974730-A | Antioxidant compound cinnamon essential oil and application | 中山大学新华学院 | 2020-04-10 | — | — | CN | disclosed |