Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21178651 | 1.00 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBIRAK4GPR6 | |
| SCHEMBL21187293 | 1.00 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBIRAK4GPR6 | |
| SCHEMBL21187285 | 0.91 | PIK3C3 (0.38) | IRAK4GPR6PDE10APRKDCTTK | |
| SCHEMBL21177867 | 0.87 | TBK1 (0.41) | IRAK4IKBKETBK1 | |
| SCHEMBL30823317 | 0.87 | TBK1 (0.41) | IRAK4IKBKETBK1 | |
| SCHEMBL22651978 | 0.87 | TBK1 (0.41) | IRAK4IKBKETBK1 | |
| SCHEMBL22635848 | 0.85 | IRAK4 (0.38) | IRAK4GPR6PDE10APRKDCTTK | |
| SCHEMBL21187357 | 0.85 | IRAK4 (0.38) | IRAK4GPR6PDE10APRKDCTTK | |
| SCHEMBL21187365 | 0.85 | PIK3C3 (0.38) | GPR6PDE10ATTKSYKIKBKE | |
| SCHEMBL21177873 | 0.85 | PIK3C3 (0.38) | GPR6PDE10ATTKSYKIKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757876-B | DNA-PK inhibitors | 沃泰克斯药物股份有限公司 | 2024-03-22 | — | — | CN | disclosed |