Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 18/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 6/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177867 | 1.00 | TBK1 (0.41) | TBK1IKBKEIRAK4JAK2JAK1 | |
| SCHEMBL22651978 | 1.00 | TBK1 (0.41) | TBK1IKBKEIRAK4JAK2JAK1 | |
| SCHEMBL21187285 | 0.90 | PIK3C3 (0.38) | TBK1IKBKEIRAK4JAK2JAK1 | |
| SCHEMBL21178651 | 0.87 | PIK3CD (0.37) | TBK1IKBKEIRAK4 | |
| SCHEMBL30823294 | 0.87 | PIK3CD (0.37) | TBK1IKBKEIRAK4 | |
| SCHEMBL21187293 | 0.87 | PIK3CD (0.37) | TBK1IKBKEIRAK4 | |
| SCHEMBL22635848 | 0.84 | IRAK4 (0.38) | TBK1IKBKEIRAK4JAK2JAK1 | |
| SCHEMBL21187357 | 0.84 | IRAK4 (0.38) | TBK1IKBKEIRAK4JAK2JAK1 | |
| SCHEMBL21177873 | 0.84 | PIK3C3 (0.38) | TBK1IKBKEJAK2JAK1JAK3 | |
| SCHEMBL21187365 | 0.84 | PIK3C3 (0.38) | TBK1IKBKEJAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757876-B | DNA-PK inhibitors | 沃泰克斯药物股份有限公司 | 2024-03-22 | — | — | CN | disclosed |