Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 11/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22418721 | 1.00 | ADRA1A (0.57) | ADRA1AHRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL30823777 | 0.84 | L3MBTL3 (0.68) | ADRA1AL3MBTL3L3MBTL1L3MBTL4MBTD1 | |
| SCHEMBL22418708 | 0.84 | L3MBTL3 (0.68) | ADRA1AL3MBTL3L3MBTL1L3MBTL4MBTD1 | |
| SCHEMBL22418675 | 0.83 | ADRA1A (0.52) | ADRA1AHRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL30823788 | 0.83 | ADRA1A (0.52) | ADRA1AHRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL22418687 | 0.81 | ADRA1A (0.54) | ADRA1A | |
| SCHEMBL30823774 | 0.81 | ADRA1A (0.54) | ADRA1A | |
| SCHEMBL22432798 | 0.81 | ADRA1A (0.56) | ADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL22432698 | 0.79 | PRMT5 (0.60) | ADRA1A | |
| SCHEMBL22418711 | 0.79 | ADRA1A (0.61) | ADRA1AL3MBTL3L3MBTL1L3MBTL4MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330009-B | Azacyclic compounds, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-09 | — | — | CN | disclosed |