Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.68 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30823777 | 1.00 | L3MBTL3 (0.68) | L3MBTL3L3MBTL1L3MBTL4MBTD1ALDH1A1 | |
| SCHEMBL22418721 | 0.84 | ADRA1A (0.57) | L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD | |
| SCHEMBL30823792 | 0.84 | ADRA1A (0.57) | L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD | |
| SCHEMBL23682703 | 0.81 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1L3MBTL4MBTD1ALDH1A1 | |
| SCHEMBL19730382 | 0.81 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1L3MBTL4MBTD1ALDH1A1 | |
| SCHEMBL22418675 | 0.81 | ADRA1A (0.52) | L3MBTL3L3MBTL1L3MBTL4MBTD1ADRA1A | |
| SCHEMBL30823788 | 0.81 | ADRA1A (0.52) | L3MBTL3L3MBTL1L3MBTL4MBTD1ADRA1A | |
| SCHEMBL22418711 | 0.81 | ADRA1A (0.61) | L3MBTL3L3MBTL1L3MBTL4MBTD1ADRA1A | |
| SCHEMBL30823775 | 0.81 | ADRA1A (0.61) | L3MBTL3L3MBTL1L3MBTL4MBTD1ADRA1A | |
| SCHEMBL23682884 | 0.80 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1L3MBTL4MBTD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330009-B | Azacyclic compounds, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-113330009-A | Nitrogen heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| WO-2020182018-A1 | NITROGEN HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2020-09-17 | — | — | WO | disclosed |
| WO-2020182018-A1 | NITROGEN HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2020-09-17 | — | — | WO | disclosed |