Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824328 | 0.80 | PARP1 (0.64) | CSNK2A1PARP1CSNK2A2CSNK2BNAMPT | |
| SCHEMBL30172793 | 0.77 | PARP1 (0.74) | CSNK2A1PARP1CSNK2A2CSNK2BNAMPT | |
| SCHEMBL10134627 | 0.74 | CSNK2A2 (0.58) | CSNK2A1PARP1CSNK2A2CSNK2BALDH1A1 | |
| SCHEMBL2690184 | 0.74 | CSNK2A2 (0.68) | CSNK2A1PARP1CSNK2A2CSNK2BDYRK1A | |
| SCHEMBL629013 | 0.74 | CSNK2A2 (0.71) | CSNK2A1PARP1CSNK2A2CSNK2BDYRK1A | |
| SCHEMBL6649135 | 0.73 | KDM4E (0.52) | PARP1KIF11MAPTKDM4EALDH1A1 | |
| SCHEMBL27165742 | 0.72 | CSNK2A1 (0.62) | CSNK2A1PARP1CSNK2A2CSNK2BDYRK1A | |
| SCHEMBL27165750 | 0.72 | CSNK2A1 (0.52) | CSNK2A1CSNK2A2CSNK2BMEN1KMT2A | |
| SCHEMBL10134619 | 0.72 | PARP1 (0.81) | CSNK2A1PARP1CSNK2A2CSNK2BKIF11 | |
| SCHEMBL16377295 | 0.71 | PARP1 (0.76) | CSNK2A1PARP1CSNK2A2CSNK2BKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11926629-B1 | Pyrido[3′,4′:4,5]pyrrolo[2,3-c]isoquinoline compounds as CK2 inhibitors | King Faisal University (SA) | 2024-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11926629-B1 | Pyrido[3′,4′:4,5]pyrrolo[2,3-c]isoquinoline compounds as CK2 inhibitors | CSNK2A3, CDK2, CSNK1G2 | CSNK2A1 7/4885PARP1 1429/4885CSNK2A2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.