Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23641873 | 0.83 | AR (0.45) | ATMARSMN1; SMN2KCNJ11MEN1 | |
| SCHEMBL15957667 | 0.83 | TRPA1 (0.50) | ATMTRPA1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL5222166 | 0.83 | SMN1; SMN2 (0.46) | ATMARSMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL15957696 | 0.82 | AR (0.50) | ATMTRPA1ARGABRA1GABRB2 | |
| SCHEMBL13199242 | 0.80 | AR (0.56) | ATMARSMN1; SMN2KCNJ11MEN1 | |
| SCHEMBL15957889 | 0.79 | TRPA1 (0.46) | ATMTRPA1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL5358414 | 0.78 | TRPA1 (0.44) | ATMTRPA1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL3821590 | 0.78 | TRPA1 (0.48) | ATMTRPA1ARGABRA1GABRB2 | |
| SCHEMBL30867018 | 0.78 | TRPA1 (0.48) | ATMTRPA1ARGABRA1GABRB2 | |
| SCHEMBL27684352 | 0.78 | TRPA1 (0.54) | ATMTRPA1SMN1; SMN2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993710-B1 | Polyimides derived from novel asymmetric benzophenone dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2015-03-31 | — | — | US | disclosed |
| US-8993710-B1 | Polyimides derived from novel asymmetric benzophenone dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2015-03-31 | — | — | US | disclosed |
| US-8809451-B2 | Fluorinated dicarboxylic acid derivative and polymer obtained therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8093348-B1 | Polyimides derived from novel asymmetric dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093348-B1 | Polyimides derived from novel asymmetric dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093348-B1 | Polyimides derived from novel asymmetric dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |
| WO-2010095678-A1 | FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM | セントラル硝子株式会社 (JP) | 2010-08-26 | — | — | WO | disclosed |
| US-7381849-B1 | Synthesis of asymmetric tetracarboxylic acids and dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-06-03 | — | — | US | disclosed |
| US-7381849-B1 | Synthesis of asymmetric tetracarboxylic acids and dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | MCCC2, AFF2, F13A1 | ATM 3040/4885TRPA1 176/4885AR 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.