Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582219 | 0.83 | MEN1 (0.52) | SMN1; SMN2KCNJ11MEN1KMT2AKDM4E | |
| SCHEMBL308249 | 0.83 | ATM (0.46) | SMN1; SMN2KCNJ11MEN1KMT2AKDM4E | |
| SCHEMBL11138245 | 0.80 | TSHR (0.47) | MEN1KMT2AMAPTALDH1A1ATM | |
| SCHEMBL9418942 | 0.80 | PDK2 (0.40) | KCNJ11KDM4ENPSR1ALDH1A1GAA | |
| SCHEMBL13324333 | 0.79 | ACHE (0.41) | KCNJ11KDM4ENPSR1ALDH1A1GAA | |
| SCHEMBL23059981 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2KCNJ11MEN1KMT2AKDM4E | |
| SCHEMBL27649195 | 0.77 | ACHE (0.40) | SMN1; SMN2KCNJ11MEN1KMT2AKDM4E | |
| SCHEMBL5362483 | 0.76 | ACHE (0.43) | KDM4ENPSR1ALDH1A1GAAATM | |
| SCHEMBL3277341 | 0.76 | ACHE (0.43) | KDM4ENPSR1ALDH1A1GAAATM | |
| SCHEMBL16105712 | 0.76 | ACHE (0.43) | KDM4ENPSR1ALDH1A1GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11785845-B2 | Composition | FUJIFILM CORPORATION (JP) | 2023-10-10 | — | — | US | disclosed |
| WO-2023171487-A1 | PHOTOSENSITIVE RESIN COMPOSITION, CURED ARTICLE, DISPLAY DEVICE, AND METHOD FOR PRODUCING DISPLAY DEVICE | 東レ株式会社 | 2023-09-14 | — | — | WO | disclosed |
| WO-2022181351-A1 | MULTILAYER BODY, DISPLAY DEVICE AND METHOD FOR PRODUCING DISPLAY DEVICE | 東レ株式会社 | 2022-09-01 | — | — | WO | disclosed |
| US-20220045283-A1 | COMPOSITION | FUJIFILM CORPORATION (JP) | 2022-02-10 | — | — | US | disclosed |
| EP-1536797-B1 | 1-AMIDO-4-PHENYL-4-BENZYLOXYMETHYL-PIPERIDINE DERIVATIVES AND RELATED COMOUNDS AS NEUROKININ-1 (NK-1) ANTAGONSISTS FOR THE TREATMENT OF EMESIS, DEPRESSION, ANXIETY AND COUGH | SCHERING CORP (US) | 2007-04-04 | — | — | EP | disclosed |
| US-7041682-B2 | NK1 antagonists | SCHERING CORPORATION (US) | 2006-05-09 | — | — | US | disclosed |
| US-20060094720-A1 | NK1 antagonists | SHIH NENG-YANG | 2006-05-04 | — | — | US | disclosed |
| EP-1536797-A1 | 1-AMIDO-4-PHENYL-4-BENZYLOXYMETHYL-PIPERIDINE DERIVATIVES AND RELATED COMOUNDS AS NEUROKININ-1 (NK-1) ANTAGONSISTS FOR THE TREATMENT OF EMESIS, DEPRESSION, ANXIETY AND COUGH | SCHERING CORPORATION (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20040072867-A1 | NK1 antagonists | SCHERING CORPORATION | 2004-04-15 | — | — | US | disclosed |
| WO-2004004722-A1 | 1-AMIDO-4-PHENYL-4-BENZYLOXYMETHYL-PIPERIDINE DERIVATIVES AND RELATED COMPOUNDS AS NEUROKININ-1(NK-1) ANTAGONISTS FOR THE TREATMENT OF EMESIS, DEPRESSION, ANXIETY AND COUGH | SCHERING CORPORATION (US) | 2004-01-15 | — | — | WO | disclosed |
| CN-1010098-B | Process for preparing alpha-fluoroacrylate polymers | HOECHST AG (DE) | 1990-10-24 | — | — | CN | disclosed |
| CN-1006380-B | Preparation method of alpha-fluoroacrylate and polymer thereof | HOECHST AG (DE) | 1990-01-10 | — | — | CN | disclosed |
| CN-1036209-A | Process for preparing alpha-fluoroacrylate polymers | HOECHST AG (DE) | 1989-10-11 | — | — | CN | disclosed |
| CN-86103531-A | Alpha-fluoroacrylates and polymers thereof | — | 1987-01-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072867-A1 | NK1 antagonists | BDKRB1, BDKRB2, MRGPRX1 | SMN1; SMN2 3913/4885KCNJ11 21/4885MEN1 1460/4885 |
| US-20220045283-A1 | COMPOSITION | ADH1A, ADH1C, SLC19A2 | SMN1; SMN2 1831/4885KCNJ11 2229/4885MEN1 740/4885 |
| US-11785845-B2 | Composition | ADH1A, ADH1C, SLC19A2 | SMN1; SMN2 1831/4885KCNJ11 2229/4885MEN1 740/4885 |
| US-20060094720-A1 | NK1 antagonists | BDKRB2, MRGPRX2, MRGPRX1 | SMN1; SMN2 4164/4885KCNJ11 98/4885MEN1 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.