Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27164391 | 1.00 | IDO1 (0.33) | IDO1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL24713026 | 0.83 | APP (0.33) | — | |
| SCHEMBL30824963 | 0.77 | ALDH1A1 (0.37) | IDO1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL30824964 | 0.77 | ALDH1A1 (0.37) | IDO1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL30824938 | 0.76 | IDO1 (0.31) | IDO1 | |
| SCHEMBL27164266 | 0.76 | IDO1 (0.31) | IDO1 | |
| SCHEMBL24713063 | 0.76 | IRAK4 (0.31) | — | |
| SCHEMBL30090427 | 0.75 | SGMS2 (0.45) | ALDH1A1MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL2245217 | 0.74 | SMN1; SMN2 (0.52) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL17544053 | 0.74 | TERT (0.39) | IDO1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545512-A | Deuterated compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2024-02-09 | — | — | CN | disclosed |