Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16188913 | 0.98 | AR (0.56) | ARCTSBMEN1KMT2AHTT | |
| SCHEMBL10963124 | 0.86 | MEN1 (0.52) | ARCTSBMEN1KMT2AHTT | |
| SCHEMBL30824991 | 0.81 | CTSB (0.56) | CTSBMEN1KMT2AHTTMAPT | |
| SCHEMBL30824956 | 0.81 | IDO1 (0.46) | ARCTSBMEN1KMT2AHTT | |
| SCHEMBL30824988 | 0.81 | DRD2 (0.54) | MEN1KMT2AL3MBTL1IDO1HTR6 | |
| SCHEMBL23484647 | 0.78 | AR (0.51) | ARCTSBMEN1KMT2AHTT | |
| SCHEMBL3602624 | 0.77 | HTR6 (0.69) | ARCTSBMEN1KMT2AHTT | |
| SCHEMBL24093676 | 0.77 | GAA (0.55) | ARCTSBMEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL30735705 | 0.76 | GAA (0.53) | ARCTSBMEN1KMT2AHTT | |
| SCHEMBL1008507 | 0.75 | GAA (0.58) | MEN1KMT2AHTTTLR9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624019-A | Naphthol [1,8-ef ] isoindole-7, 8,10 (9H) -trione derivative and preparation method and application thereof | 华侨大学 | 2024-03-01 | — | — | CN | disclosed |