Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC27A2 | O14975 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185410 | 1.00 | GAA (0.47) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL1307887 | 0.80 | PDK2 (0.47) | LMNAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL29540116 | 0.80 | PDK2 (0.47) | LMNAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL29716665 | 0.79 | PDK2 (0.47) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL20138592 | 0.77 | PGR (0.45) | GAALMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL13833088 | 0.77 | GAA (0.47) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL31072306 | 0.77 | MAPT (0.48) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL19318176 | 0.76 | LMNA (0.60) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL18032791 | 0.76 | KDM4E (0.44) | LMNAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL18362651 | 0.76 | LMNA (0.50) | GAAMGAMSIMGAM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683019-A | Bromination method of 9, 10-dihydroacridine derivative | 郑州原理生物科技有限公司 | 2024-03-12 | — | — | CN | disclosed |